Name | DL-Tyrosine |
Synonyms | DL-Tyrosine DL-TYROSINE extrapure CHR (±)-3-(p-Hydroxyphenyl)alanine 3-(4-Hydroxyphenyl)-DL-alanine DL-α-AMino-β-p-hydroxyphenylpropionic acid 3-(4-Hydroxyphenyl)-DL-alanine~H-DL-Tyr-OH (à)-2-Amino-3-(4-hydroxyphenyl)propionic acid rac-(R*)-2-Amino-3-(p-hydroxyphenyl)propionic acid (±)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-DL-alanine |
CAS | 556-03-6 |
EINECS | 209-113-1 |
InChI | InChI=1/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13) |
Molecular Formula | C9H11NO3 |
Molar Mass | 181.19 |
Density | 1.2375 (rough estimate) |
Melting Point | ≥300 °C (lit.) |
Boling Point | 314.29°C (rough estimate) |
Water Solubility | Soluble in water. |
Solubility | Soluble in alkali solution and dilute acid, hardly soluble in water, insoluble in acetone, ethanol and ether |
Appearance | White crystal |
Color | White to Off-White |
Merck | 14,9839 |
BRN | 515881 |
pKa | pK1:2.18(+1);pK2:9.11(0);pK3:10.6(OH) (25°C) |
Storage Condition | Store at RT. |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Sensitive to light |
Refractive Index | 1.5270 (estimate) |
MDL | MFCD00063074 |
Physical and Chemical Properties | White fine needle Crystal, odorless, bitter taste; Soluble in alkali solution and dilute acid, insoluble in water, insoluble in acetone, ethanol and ether; Decomposition point of 316 ℃. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29225000 |
Reference Show more | 1. Li Nan, Mao Qing, Zhou Xue-Xue, Qi Ya-Jie. Preparation of a whitening cream [J]. Heilongjiang Science, 2021,12(04):26-27 31. 2. Zhang Lei, Feng Chen, Yang Shuqin, Guo Shuru. Study on the efficacy of a compound plant extract against ultraviolet and blue light [J]. Journal of Daily Chemical Science, 2021,44(04):44-48. 3. [IF = 7.46] Ye Zhang et al."A dual-signal sensing platform based on nanosheet materials for rational flux and colormetric detection of enzyme activities in human blood." Sensor Actuat B- Chem. 2021 Nov;346:130531 4. [IF = 4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning." J Food Compos Anal. 2020 May;88:103460 5. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10 6. [IF=3.361] Ning Zhao et al."Ratiometric fluorescence probe of Cu2 and biothiols by using carbon dots and copper nanoclusters."Rsc Adv. 2021 Oct;11(53):33662-33674 7. [IF=4.242] Hang Yang et al."Dietary leucine requirement of juvenile largemouth bass (Micropterus salmoides) based on growth, nutrient utilization and growth-related gene analyses."Aquaculture. 2022 Jun;555:738207 8. [IF=3.935] Min Zhang et al."Chemical profile and miscarriage prevention evaluation of Jiao-ai decoction, a classical traditional Chinese formula."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 May;:114832 9. [IF=2.281] Zihui Ma et al."Studies on the biosynthetic pathways of melanin in Auricularia auricula."JOURNAL OF BASIC MICROBIOLOGY |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | DL-Tyrosine is an aromatic non-essential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is the precursor of several important neurotransmitters (epinephrine, norepinephrine, dopamine). |
Use | for biochemical studies. |
production method | L-tyrosine is used as raw material, acetic anhydride is added for acylation reaction to obtain O,N-diacetyl-L-tyrosine, O,N-diacetyl-L-tyrosine was hydrolyzed with hydrochloric acid and treated with activated carbon to obtain a pure product. |